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Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.

Overdose

Contact your doctor if an overdose is suspected. Symptoms of overdose may include nausea, vomiting, or vaginal bleeding.

Interactions

Carbamazepine   (moderate)

Dexamethasone   (moderate)

Prednisolone   (moderate)

Tranexamic Acid   (severe)

Warfarin   (moderate)

Thalidomide   (severe)

Prescribes

Post menopausal symptoms

This medicine is used to relieve and treat the symptoms experienced after menopause. Most common symptoms include hot flashes and vaginal dryness.

Vaginal/vulvar atrophy

This medicine is used to treat vaginal atrophy marked by thinning and shrinking of tissues in the urethra and the vagina and decreased lubrication due to lack of hormone estrogen.

Hypoestrogenism

This medicine is used to treat hypoestrogenism characterized by low estrogen levels and associated side effects. This may be due to castration, hypogonadism, or failure of the ovaries.

Primary ovarian failure

This medicine is used to treat the symptoms of primary ovarian failure which results in low estrogen level in the body and infertility.

End-stage breast cancer

This medicine is used to manage the symptoms of breast cancer that has spread to other parts of the body.

Postmenopausal osteoporosis

This medicine is also used to prevent and treat the symptoms of osteoporosis in women who have reached menopause.

Prostate Cancer

This medicine is also used for the management of symptoms of prostate cancer.

Oophorectomy

This medicine is also used while and after the patient undergoes a surgery to remove one or both the ovaries.

Side Effects

Breast pain and tenderness  

Vomiting  

Weight gain  

Dizziness  

Depression  

Back pain  

Headache  

Vaginal discharge with no odor  

Flu like symptoms  

Excessive vaginal bleeding   (severe)

Swelling of face, lips, eyelids, tongue, hands and feet   (severe)

Troubled breathing and swallowing   (severe)

Discharge from the nipple   (severe)

Change in the texture of breast skin and nipples   (severe)

Inverted nipples   (severe)

Warnings

Abnormal vaginal bleeding

Cardiovascular risks

Dementia

Breast cancer

Jaundice

Surgery

Oedema

Difference in vision

Gall bladder disease

Formation of blood clots

Pediatric use

Pregnancy

Breast-feeding

When Not To Use

Allergy

This medicine is not recommended for use in patients who have a known allergy to estrogen products or any other ingredient present along with it.

Undiagnosed vaginal bleeding

This medicine is not recommended for use if you have an abnormal episode of vaginal bleeding which was not diagnosed.

Heart and blood vessel disorder

This medicine is not recommended for use in patients having a disease of the heart or blood vessels viz. deep vein thrombosis, recent heart attack, other blood clotting disorders etc.

Breast cancer

This medicine is not recommended for use in patients having breast cancer. It should also not be used if a patient has had breast cancer before or is suspected of having it. Patients having end stage breast cancer and on palliative care are an exception here.

Estrogen-dependent tumor

This medicine is not recommended for use in patients having cancer which is attributed to abnormal levels of the hormone estrogen in the body for prolonged duration.

Liver disease

This medicine is not recommended for use in patients having an impairment of liver function owing to a disease or other contributing factors.