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Dosage

Missed Dose

If a dose of PDgrastim Injection 300 mcg 1 Vial is missed, take the dose as soon as you remember. If it is almost the time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Cisplatin   (moderate)

Fluorouracil   (moderate)

Doxorubicin   (moderate)

Prescribes

Neutropenia caused by chemotherapy

PDgrastim Injection 300 mcg 1 Vial is used to reduce the incidence of infection in patients receiving myelosuppressive anti-cancer drugs.

Bone Marrow Transplantation

This medicine is used to treat febrile neutropenia, the fever caused due to decreased neutrophil count in patients receiving chemotherapy followed by bone marrow transplantation.

Peripheral Progenitor Cell Transplantation

This medicine is used before the procedure of leukapheresis to mobilize the autologus hematopoietic progenitor cells into the peripheral blood for collection.

Chronic Neutropenia

PDgrastim Injection 300 mcg 1 Vial is used to reduce the incidence of infection, fever, and oropharyngeal ulcers in patients with chronic neutropenia.

Neutropenia caused by radiation

PDgrastim Injection 300 mcg 1 Vial is used to increase the survival rate in patients who have received high doses of myelosuppressive radiation.

Side Effects

Stomach pain   (severe)

Hair loss   (severe)

Constipation   (severe)

Nausea or Vomiting   (severe)

Fever and chills   (severe)

Bone pain   (severe)

Loss of appetite  

Weight loss  

Swelling or inflammation of mouth  

Warnings

Splenic Rupture

Acute Respiratory Distress Syndrome (ARDS)

Sickle cell crisis

Pregnancy

Breast-feeding

When Not To Use

Allergy

This medicine is not recommended for use in patients with a known allergy to PDgrastim Injection 300 mcg 1 Vial and peg PDgrastim Injection 300 mcg 1 Vial products.