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Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek the emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Carbamazepine   (moderate)

Ciprofloxacin   (moderate)

Cyclosporine   (moderate)

Colchicine   (severe)

Cholestyramine   (moderate)

Fenofibrate   (moderate)

Ketoconazole   (severe)

HIV protease inhibitors   (severe)

Prescribes

Primary Hypercholesterolemia

This medicine is used to treat primary hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood.

Hyperlipidemia

This medicine is used to treat hyperlipidemia, a condition characterized by high levels of lipids in the blood.

Side Effects

Dizziness   (severe)

Fast heartbeat   (severe)

Dark colored urine   (severe)

Muscle or joint pain   (severe)

Sweating   (severe)

Headache   (severe)

Acid or sour stomach  

Excessive air or gas in stomach  

Heartburn  

Skin Rash  

Sore throat   (severe)

Runny Nose   (severe)

Sneezing  

Itching  

Loss of appetite  

Fever  

Cough   (severe)

Nausea and Vomiting  

Warnings

Cognitive impairment

Liver enzymes

Myopathy and Rhabdomyolysis

Alcohol consumption

Fusidic acid

Coumarin Anticoagulants

Pediatric use

Other medicines

Pregnancy

Breast-feeding

When Not To Use

Allergy

This medicine is not recommended for use in patients with a known allergy to simvastatin, ezetimibe, or any other inactive ingredients present along with these medicines.

Impaired Liver function

This medicine is not recommended for use in patients with active liver diseases or any abnormality in the liver function tests due to the increased risk of severe adverse effects. It is also not recommended for use in patients with a moderate-to-severe liver function impairment due to the increased risk of worsening of the patient's condition.