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Dosage

Missed Dose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

Amikacin   (Moderate)

Ethinyl Estradiol   (Moderate)

Cholera Vaccine   (Severe)

Cyclosporine   (Moderate)

Prescribes

Bacterial Meningitis

SAFIPHIN 250mg Injection Per Vial is used in the treatment of meningitis, which is an inflammation of the protective membranes that surround the brain and spinal cord. This infection may be caused by Streptococcus pneumoniae or Neisseria meningitidis.

Bacterial Septicemia

SAFIPHIN 250mg Injection Per Vial is used in the treatment of septicemia which is an infection of the blood caused by Staphylococci and Streptococcus pyogenes.

Gonococcal Infection

SAFIPHIN 250mg Injection Per Vial is used in the treatment of gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

Urinary Tract Infection

SAFIPHIN 250mg Injection Per Vial is used in the treatment of infections of the urinary tract caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

Pneumonia

SAFIPHIN 250mg Injection Per Vial is used in the treatment of community-acquired pneumonia which is a common type of lung infection caused by Streptococcus pneumoniae and Haemophilus influenzae.

Bone and joint infections

SAFIPHIN 250mg Injection Per Vial is used in the treatment of bone and joint infections such as septic arthritis and osteomyelitis caused by Staphylococci and Streptococci species.

Skin and structure Infection

SAFIPHIN 250mg Injection Per Vial is used in the treatment of Skin and structure infections such as cellulitis, wound infection and cutaneous abscesses caused by Streptococcus pyogenes and Staphylococcus aureus.

Side Effects

Black or tarry stools   (Severe)

Chest pain   (Severe)

Fever   (severe)

Difficulty or painful urination   (severe)

Sore throat   (severe)

Diarrhea   (severe)

Abdominal pain   (severe)

Dizziness   (severe)

Swelling of face, lips, eyelids, tongue, hands and feet   (severe)

Acid or sour stomach   (severe)

Change in taste   (rare)

Excessive air or gas in stomach   (rare)

Warnings

Allergy

Hemolytic anemia

Prothrombin time

Drug-resistance

Patients with impaired kidney or liver function

Clostridium difficile-associated Diarrhea

Use in neonates

Pregnancy

Breast-feeding

When Not To Use

Allergy

This medicine is not recommended for use in patients with a known allergy to SAFIPHIN 250mg Injection Per Vial or any other Beta-lactam antibiotics such as penicillins or cephalosporins.

Lidocaine

SAFIPHIN 250mg Injection Per Vial is contraindicated for use if Lidocaine is used as a solvent for intravenous injection. Lidocaine can be used as a solvent for the intramuscular route of injection for this medicine, despite contraindications.

Calcium-containing products

SAFIPHIN 250mg Injection Per Vial is contraindicated in neonates who are on calcium-containing intravenous solutions or infusions such as parenteral nutrition because of the risk of precipitation of SAFIPHIN 250mg Injection Per Vial and calcium.