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Dosage

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

Dexamethasone   (moderate)

Aliskiren   (severe)

Captopril   (severe)

Insulin   (moderate)

Antidepressants   (moderate)

Nonsteroidal anti-inflammatory medicines   (moderate)

Prescribes

Essential hypertension

This medicine is used in the treatment of high blood pressure which may be caused by genetic or environmental factors.

Side Effects

Increased urination   (severe)

Itching or rash  

Abdominal and stomach pain  

Dry mouth   (severe)

Myalgia  

Chest pain   (severe)

Nausea and Vomiting  

Cough   (severe)

Headache  

Chills   (severe)

Nasal congestion   (severe)

Unusual tiredness and weakness  

Blood in urine   (severe)

Joint pain   (severe)

Swelling of feet or lower legs   (severe)

Bladder pain   (severe)

Diarrhea  

Dizziness   (severe)

Warnings

Hepatic dysfunction

Volume and electrolyte depletion

Renal diseases

Hypotension

Hyperkalemia

Systemic Lupus Erythematosus

Pediatric population

Eye diseases

Use in athletes

Pregnancy

Breast-feeding

When Not To Use

Allergy

This medicine is not recommended for use in patients with a known allergy to hydrochlorothiazide, other sulfonamides, olmesartan, or any other angiotensin receptor blockers.

Anuria

This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.

Aliskiren

Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment (CrCl < 30 ml/min) due to the increased risk of serious adverse effects.